Acne SSS ( Salicylic Acid 2% / Sulfacetamide Sodium 10%/ Sulfur 2.5%) Lotion

Salicylic Acid
Salicylic acid is a topical keratolytic agent. It is used to remove excess keratin in hyperkeratotic skin disorders such as common and plantar warts, psoriasis, seborrheic dermatitis, calluses, and corns. Salicylic acid also is used to treat acne. Salicylic acid works by causing desquamation of the horny layer of skin. Prolonged or repeated daily use over large areas of skin may result in salicylism, especially in children and patients with renal or hepatic impairment. This drug was approved by the FDA in 1939.

Sulfacetamide
Sulfacetamide is a synthetic sulfonamide antibiotic for ophthalmic or topical administration. Sulfacetamide, because it is water soluble and because a 30% solution has a pH of 7.4, is an ideal sulfonamide for ophthalmic administration. Despite the favorable pharmaceutical properties, the use of sulfonamides, in general, has declined due to the development of resistance. Sulfacetamide is used topically for the treatment of acne, scaling dermatoses such as seborrheic dermatitis and seborrheic sicca, and also for a topical bacterial skin infection caused by susceptible organisms. Sulfacetamide was approved by the FDA in 1946 for the treatment of conjunctivitis, corneal ulcers, and other superficial eye infections caused by susceptible organisms.